Introduction

Radiculopathy, also known as “pinched nerve,” is a painful condition that occurs when one of the spinal nerve roots is compressed or irritated where it emerges from the spinal canal. This compression can lead to a range of symptoms, including pain, numbness, tingling and muscle weakness in the corresponding region of the body.

The main cause of radiculopathy is compression of the nerve roots due to various factors. Common causes include herniated discs, bone spurs, spinal stenoses, inflammation from conditions such as arthritis, and spinal trauma. These factors contribute to pressure on the nerve root, causing disruption in the transmission of nerve signals and generating painful symptoms.

Radiculopathy can occur at any level of the spine, but when it occurs in the neck, it is referred to as cervical radiculopathy. Cervical nerve roots, originating from the spinal cord in the neck region, are susceptible to compression from conditions such as herniated discs or cervical spondylosis.

Symptoms of cervical radiculopathy can vary depending on the nerve root affected and the severity of the compression. Patients may experience radiating pain down the arm, numbness or tingling in the fingers, and muscle weakness in the neck or shoulder area. Neck movement may also be limited due to pain and stiffness.

Diagnosing cervical radiculopathy usually involves a thorough evaluation of the patient’s medical history, a physical examination, and imaging tests such as X-rays, MRIs, or CT scans. These tests help locate the source of the compression and determine the extent of the damage.

Treatment for cervical radiculopathy aims to relieve pressure on the nerve root, reduce inflammation, and alleviate symptoms. Treatment approaches may include taking anti-inflammatory medications, osteopathy to strengthen neck muscles and improve mobility, and corticosteroid injections to reduce local inflammation.

In more severe cases or when conservative treatments are not effective, surgery may be considered to release pressure on the nerve root. However, surgery is usually only considered after other treatment options have been exhausted and when symptoms persist or worsen.

So, cervical radiculopathy is a painful condition resulting from compression of a nerve root in the neck region. Management of this condition requires an individualized approach, often combining medications, physical therapy, and in some cases, surgical procedures. Early diagnosis and a proper treatment plan are essential to minimize symptoms and improve the quality of life of those affected by this condition.

Example of spinal cord compression (red letter)
The C6 and C7 nerve roots are most commonly affected. Patients younger than 55 years are more likely to experience radiculopathy resulting from acute disc herniation, while those older than 55 years are more likely to experience symptoms resulting from degenerative foramen stenosis.

Example of spinal cord compression (red letter)

Causes of cervical radiculopathy

The causes of cervical radiculopathy can vary, and their significance may depend on several factors. Here are some of the common causes of cervical radiculopathy, presented in descending order of frequency:

  1. Cervical disc herniation: A herniated disc in the cervical region, where the intervertebral disc puts pressure on the nerve roots, is a common cause of cervical radiculopathy.
  2. Cervical osteoarthritis (spondylosis): Osteoarthritis, or wear and tear of the joints, can cause the formation of small bony growths (osteophytes) that compress nerve roots.
  3. Bone spur (osteophyte): Abnormal bone growth can put pressure on nerve roots, causing radiculopathy.
  4. Cervical Stenosis: Stenosis, a narrowing of the spinal canal in the cervical spine, can compress nerve roots and cause symptoms of radiculopathy.
  5. Traumatic cervical injuries: Injuries, such as sprains, dislocations, or fractures of the cervical spine, can result in compression of the nerve roots.
  6. Tumors: Tumors of the cervical spine can compress nerve roots and cause radiculopathy, although this is less common.
  7. Infections: Infections of the spine or intervertebral discs can lead to inflammation and compression of nerve roots.
  8. Birth defects: Some people may have birth defects of the cervical spine that increase the risk of radiculopathy.

It is important to note that several of these factors may coexist in an individual, and the severity of radiculopathy may vary depending on the underlying cause.

Symptoms of cervical radiculopathy

Symptoms of cervical radiculopathy may vary depending on the severity of the compression or irritation of the nerve roots in the cervical region of the spine. Here is a list of symptoms commonly associated with cervical radiculopathy, presented in decreasing order of frequency:

  1. Radicular pain: Pain is often the most predominant symptom. It can radiate from the neck to the arm, shoulder, or even the fingers. The pain usually follows the path of a specific nerve root.
  2. Tingling or numbness: Sensations of tingling, numbness, or tingling may be felt in the neck, shoulder, arm, or fingers. These sensations are often linked to nerve compression.
  3. Muscle weakness: Compression of nerve roots can lead to muscle weakness in the arm or hand corresponding to the affected root.
  4. Decreased sensitivity: Decreased sensitivity, sometimes described as loss of sensation, may occur in the area innervated by the compressed nerve root.
  5. Neck Pain: Pain can also be felt in the neck area itself, especially near the spine.
  6. Decreased reflexes: Compression of nerve roots can cause decreased reflexes in the affected area.
  7. Difficulty performing certain activities: Symptoms may be exacerbated during certain activities, such as raising your arm or turning your head.
  8. Neck Stiffness: Stiffness in the neck may be experienced, particularly if radiculopathy is associated with other cervical spine problems, such as osteoarthritis.

It is important to note that symptoms can vary from person to person, and not all symptoms are present in every individual with cervical radiculopathy.

C7 radiculopathy

Patients experiencing C7 radiculopathy commonly adopt a distinctive posture to alleviate their symptoms. This frequently involves placing the hand of the affected extremity on the head in an attempt to find relief. The specific gesture of placing the hand on the head serves as a natural response to the discomfort and pain associated with C7 radiculopathy.

C7 radiculopathy refers to the compression or irritation of the C7 nerve root, which is situated in the cervical (neck) region of the spine. The C7 nerve root is a component of the brachial plexus, a network of nerves that extends from the neck down to the arm. When this nerve root is affected, it can lead to radiating pain, weakness, or numbness along the path of the nerve, often extending into the arm and hand.

Placing the hand on the head is a positional strategy that patients instinctively adopt to reduce the pressure on the affected nerve and mitigate the associated discomfort. By doing so, individuals may inadvertently relieve tension on the nerve roots and find temporary relief from the symptoms. This gesture is reflective of the body’s natural inclination to find a position that minimizes the stress on the affected nerves.

It’s important to note that while this posture might provide momentary relief, it doesn’t address the root cause of C7 radiculopathy. Seeking professional medical evaluation and diagnosis is crucial for understanding the underlying issues and determining an appropriate course of treatment. Treatment options may include physical therapy, medication, and, in some cases, surgical intervention, depending on the severity and nature of the condition.

Pathophysiology

The main pathophysiological mechanisms of cervical radiculopathy include:

  1. Nerve Root Compression: The root cause of cervical radiculopathy is nerve root compression. This compression can result from a variety of conditions, including herniated discs, bone spurs, spinal stenoses, arthritis-related inflammation, or spinal trauma. Compression causes disruption in the transmission of nerve signals.
  2. Herniated disc: When an intervertebral disc, which acts as a cushion between the vertebrae, herniates or moves from its normal position, it can put pressure on the cervical nerve roots. This can cause inflammation and irritation of the nerves.
  3. Bone spurs (osteophytes): Abnormal growth of bone, in the form of bone spurs, can occur as a result of normal wear and tear of joints (osteoarthritis). These bone spurs can compress nerve roots and contribute to the symptoms of radiculopathy.
  4. Spinal Stenosis: A reduction in the space in the spinal canal, called spinal stenosis, can lead to compression of the cervical nerve roots. This condition can result from osteoarthritis, thickening of ligaments or abnormal bone growth.
  5. Inflammation: Inflammatory conditions, such as arthritis, can lead to inflammation of the structures around nerve roots. Inflammation contributes to compression and irritation of the nerves.
  6. Spinal Trauma: Injuries, such as car accidents or falls, can cause damage to spinal structures, leading to compression of nerve roots.

Acute disc herniation (spondylosis)

Cervical spondylosis begins with drying out of the disc. The avascular disc loses water due to a decrease in proteoglycan content in the nucleus pulposus, which leads to a decrease in water content from 90% at birth to 74% during the eighth decade of life. This change leads to loss of disc height, microinstability and consequent osteophyte formation, facet hypertrophy, and buckling and hypertrophy of the ligamentum flavum. Spinal degeneration, or spondylosis, can lead to neuroforaminal stenosis and potentially spinal canal stenosis.

Therapeutic recommendations

It is important to note that the effectiveness of osteopathy can vary from person to person, and its use often depends on the underlying cause of the radiculopathy and the individual response to treatment. Here are recommendations, including osteopathy, for cervical radiculopathy:

  1. Pain management:
    • Use nonsteroidal anti-inflammatory drugs (NSAIDs) or other pain relievers as recommended by your healthcare professional.
  2. Osteopathy:
    • Consult a qualified osteopath for specific manual manipulations aimed at restoring neck mobility, relieving pressure on nerve roots and improving overall function.
  3. Lifestyle changes:
    • Practice good posture at work and at home.
    • Avoid positions and activities that make symptoms worse.
  4. Cervical orthoses:
    • In some cases, wearing a cervical collar may be recommended to limit neck movement and allow nerve roots to heal.

Differential diagnostics

  1. Thoracic outlet syndrome: This condition results from compression of blood vessels or nerves in the thoracic outlet area, leading to symptoms such as pain and numbness in the arm.
  2. Cervical Osteoarthritis: Osteoarthritis of the cervical joints can cause neck pain and radiation into the arms, which can be confused with the symptoms of cervical radiculopathy.
  3. Cauda Equina Syndrome: Although more common in the lumbar region, cauda equina syndrome can cause compression of nerve roots in the cervical region, resulting in symptoms similar to radiculopathy.
  4. Cervical meningitis: Inflammation of the membranes surrounding the spinal cord can cause symptoms similar to cervical radiculopathy, such as headaches, neck stiffness, and radiating pain.
  5. Cervical tumors: Tumors of the spine or surrounding tissues can compress cervical nerve roots, causing symptoms similar to radiculopathy.
  6. Herniated cervical disc: A herniated disc can put pressure on the cervical nerve roots, causing pain and numbness in the arms.

Radiographic signs

Radiographic signs of cervical radiculopathy can be seen through different medical imaging tests, such as x-rays, MRI (magnetic resonance imaging) or CT scans. These signs can indicate changes in the cervical spine and offer clues to the presence of nerve compression. Here are some of the radiographic signs that healthcare professionals can look for when evaluating cervical radiculopathy:

  1. Narrowing of the spinal canal: Narrowing of the cervical spinal canal may be seen on x-rays, indicating cervical stenosis, which may contribute to nerve root compression.
  2. Herniated disc: A herniated cervical disc can be seen on an MRI. It manifests itself by a protrusion or protrusion of the intervertebral disc into the space occupied by the nerve roots.
  3. Osteophytes (many called “bone spurs”): Bony growths can develop along the edges of the vertebrae, often resulting from osteoarthritis. These osteophytes can put pressure on nerve roots.
  4. Enlargement of the foramen: The foramen, through which nerve roots exit the spine, may show signs of enlargement due to nerve compression.
  5. Vertebral displacement or instability: Instability or abnormal displacement of the vertebrae may be visible on x-rays.
  6. Subchondral sclerosis: Thickening or densification of the bone beneath the cartilage (subchondral sclerosis) may indicate degenerative changes.
  7. Alterations in Cervical Lordosis: Changes in the natural curvature of the cervical spine, such as loss of cervical lordosis, may be noted.

It is important to note that radiographic signs may vary depending on the stage of cervical radiculopathy and the severity of structural changes.

Conclusion

In conclusion, cervical radiculopathy, or “pinched nerve” in the neck, represents a potentially disabling condition resulting from compression of a nerve root emerging from the spinal canal. Various symptoms, such as pain, numbness and muscle weakness, can significantly impair the quality of life of affected individuals.

The causes of cervical radiculopathy are diverse, ranging from herniated discs to bone spurs to spinal stenoses. These compression factors contribute to the disruption of nerve signals, thereby generating a range of symptoms specific to the cervical region.

Diagnosis of this condition is based on a thorough clinical assessment, supported by imaging tests such as x-rays and MRIs. Once diagnosed, management of cervical radiculopathy often involves a stepwise approach, starting with conservative treatments such as anti-inflammatory medications, physical therapy, and corticosteroid injections.

However, in cases that are more complex or resistant to non-surgical treatments, surgery may be considered to release the compressed nerve root. This highlights the importance of close collaboration between the patient and the medical team to determine the best therapeutic approach suited to each case.

Cervical radiculopathy highlights the importance of increased awareness of symptoms and seeking early medical evaluation for persistent pain in the neck, shoulders, or arms. Developing a personalized treatment plan, taking into account the severity of symptoms and underlying causes, is crucial to minimizing the impact of this condition on daily life.

Ultimately, an integrated approach, combining medical, physiotherapeutic and sometimes surgical interventions, offers promising prospects in the management of cervical radiculopathy. Improving understanding of this condition and access to appropriate care play a crucial role in improving the quality of life of individuals facing this medical challenge.

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